Dr. Chris Parker is Consultant in Clinical Oncology at the Royal Marsden Hospital.  Introduction: Until recently, it was widely recommended that men with an elevated serum prostate-specific antigen (PSA) level should routinely have a prostate biopsy. However, the use of a PSA threshold to identify men for prostate biopsy has been questioned since the Prostate Cancer Prevention Trial showed that the risk of finding prostate cancer on biopsy was associated with not just PSA level, but also with digital...