Dr. Isabel Cunningham is Attending Physician, Mount Sinai Hospital at Queens Hospital Center; Adjunct Associate Research Scientist, Division of Oncology, Columbia University College of Physicians and Surgeons. View profile. 1. In your view, which development that has occurred since September 2007 could have the most significant impact on oncology? The results of this century’s new targeted agents against myeloma, now used in combination protocols in newly diagnosed patients, are giving hope that...