NEWS

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ASCO GU to Spotlight Prostate Cancer Drugs MDV3100 and Radium-223

S London, 2012 Feb 1, Elsevier Global Medical News

The 2012 Genitourinary Cancers Symposium, to be held Feb. 2-4, will feature potentially practice-changing data on two novel agents – MDV3100 and radium-223 chloride – in prostate cancer. * Results of the...

NICE Issues Early 'No' on Abiraterone

J Smith, 2012 Feb 1, Elsevier Global Medical News

The cost effectiveness agency for England and Wales said that it would not recommend abiraterone, a drug considered to be a breakthrough second-line treatment for men with castration-resistant metastatic...

FDA Adds Longer GIST Therapy to Imatinib Label

E Mechcatie, 2012 Feb 1, Elsevier Global Medical News

Clinical trial data showing a significant increase in survival when imatinib is used for 3 years as adjuvant therapy after resection of Kit-positive gastrointestinal stromal tumors has been added to the...

Brivanib Disappoints in Metastatic KRAS Wild-Type Colorectal Cancer

S London, 2012 Jan 30, Elsevier Global Medical News

SAN FRANCISCO – Eagerly awaited results of the CO.20 trial in metastatic chemorefractory KRAS wild-type colorectal cancer are disappointing, showing no significant gain in the primary endpoint of overall...

PET/CT Detects Early Recurrence of Head and Neck Cancer

ME Tucker, 2012 Jan 30, Elsevier Global Medical News

PHOENIX (EGMN) - Routine use of positron emission tomography/computed tomography scans can detect locoregional recurrences of squamous cell carcinoma of the head and neck before they became clinically...

Vismodegib Receives FDA Approval for Metastatic BCC

A Ault, 2012 Jan 30, Elsevier Global Medical News

The Food and Drug Administration has approved vismodegib, an oral, once-daily medication for adults with locally advanced and metastatic advanced basal cell carcinoma on Jan. 30.Vismodegib (Erivedge) is...

Metformin May Lower Pancreatic Cancer Risk in Women

S Worcester, 2012 Jan 30, Elsevier Global Medical News

Metformin use was associated with a decreased risk of pancreatic cancer in women, but not in men, in a large case-control study involving more than 19,300 U.K. primary care patients.Additionally, use of...

Inlyta Approval Expands Pfizer Kidney Cancer Options, But With Unique Safety Profile

S Haley, 2012 Jan 27, The Pink Sheet Daily

FDA’s approval of Pfizer Inc.’s oral second generation VEGF inhibitor Inlyta (axitinib) for advanced kidney cancer appears to have been motivated not as much by its superiority in a head-to-head comparison...

Malignancy Rates Remain Stable in Ustekinumab-Treated Patients

H Splete, 2012 Jan 27, Elsevier Global Medical News

RIO GRANDE, P . R . (EGMN) - Malignancy rates in psoriasis patients treated with ustekinumab did not increase significantly over 4 years of follow-up, based on pooled data from 3,117 patients enrolled...

Erlotinib Dose Doubled for Smokers With Head and Neck Cancer

ME Tucker, 2012 Jan 27, Elsevier Global Medical News

PHOENIX (EGMN) - Giving smokers a higher, short-course dose of erlotinib before definitive surgery for squamous cell carcinoma of the head and neck resulted in favorable responses for the first patients...