Tasigna Beats Sprycel to First-Line CML Punch

The Pink Sheet Daily. 2010 Jul 5, J Merrill

Now that Novartis' Tasigna (nilotinib) has been approved by FDA for the treatment of first-line chronic myeloid leukemia, the race has officially begun for two second-generation BCR-ABL kinase inhibitors to supplant the venerable market-leader, Novartis' Gleevec (imatinib). The other competitor expected soon to be vying for a piece of the first-line market is Bristol-Myers Squibb with its Sprycel (dasatinib). That drug, approved since 2006 for second-line CML, has not yet been cleared for first line...

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