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Meta-Analysis Shows No Benefit for High-Dose Chemotherapy in Breast Cancer
No Benefit From High-Dose Chemo in Breast Cancer
B. Jancin
20080002
2008 Jan 2
Elsevier Global Medical News
Meta-Analysis Shows No Benefit for High-Dose Chemotherapy in Breast Cancer
Elsevier Global Medical News. 2008 Jan 2, B. Jancin
SAN ANTONIO (EGMN) -- High-dose chemotherapy supported by autologous stem cell transplantation resulted in no overall survival benefit over standard-dose adjuvant chemotherapy in women with node-positive breast cancer in a comprehensive meta-analysis of 15 randomized clinical trials.Moreover, study investigators could not identify a subset of patients who benefitted from this intensive, costly, arduous, and controversial therapy based upon age, menopausal status, number of positive lymph nodes, tumor...