Patients with esophageal adenocarcinoma and esophagogastric junction adenocarcinoma were significantly less likely than population controls to have evidence of past Helicobacter pylori infection, Dr. David C. Whiteman and his colleagues reported in the July issue of Gastroenterology. The association persisted independently of known esophageal cancer risk factors, such as reflux and smoking, and also was independent of genetic factors, including polymorphisms in genes coding for interleukin-1B and...