The Food and Drug Administration issued an alert on Jan. 7 about the possibility that patients on bisphosphonates can develop severe musculoskeletal pain, starting within days, months, or even years after initiating treatment.Although the precautions section of the prescribing information for all drugs in this class lists severe musculoskeletal pain as a potential side effect, "the association between bisphosphonates and severe musculoskeletal pain may be overlooked by health care professionals,...