FDA Approves Rasburicase as Initial Therapy for Adults at Risk for Tumor Lysis Syndrome

OncologySTAT Editorial Team. 2009 Oct 20, E Okin Powers

On October 16, the US Food and Drug Administration gave its stamp of approval for a new indication for rasburicase. The recombinant uricolytic agent can now be used in the initial management of plasma uric acid (PUA) levels in adult patients with leukemia, lymphoma, and solid tumor malignancies who are receiving anticancer therapy expected to cause elevations of plasma uric acid and lead to the development of the tumor lysis syndrome (TLS). Tumor lysis syndrome is a potentially life-threatening...

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