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Early Look at Ki67 May ID Nonresponders to Neoadjuvant Estrogen Therapy
Early Look at Ki67 May ID Nonresponders to Neoadjuvant Estrogen Therapy
B Bates
20100006
2010 Jan 6
Elsevier Global Medical News
Early Look at Ki67 May ID Nonresponders to Neoadjuvant Estrogen Therapy
Elsevier Global Medical News. 2010 Jan 6, B Bates
SAN ANTONIO (EGMN) - Analysis of the biomarker Ki67 from a tumor biopsy obtained just 2-4 weeks into neoadjuvant endocrine therapy may provide valuable insight into therapeutic response among postmenopausal women with estrogen receptor-positive, HER2-negative breast cancer.In two trials, patients with a tumor Ki67 cut point value greater than 10% after undergoing a few weeks of endocrine therapy were found to have significantly poorer outcomes than did those whose biomarker expression was low, Dr....