Anthracyclines Called Into Question in Breast Cancer

Elsevier Global Medical News. 2008 Jan 15, B. Jancin

SAN ANTONIO (EGMN) - The anthracyclines, in recent decades the mainstay of adjuvant chemotherapy for breast cancer, should now assume a greatly reduced role in treatment, Dr. Dennis Slamon asserted at the annual San Antonio Breast Cancer Symposium. The anthracyclines are notoriously cardiotoxic. They also cause leukemia. Physicians and patients were willing to assume those risks because of presumed greater efficacy. But recent evidence indicates the efficacy of anthracyclines is superior to that...

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