Having trouble viewing the email? View it here.

A Week in Review
Sign up for this newsletter »Read more at Oncologystat.com »October 14, 2009 | Issue 90

Scan of the Week
Dasatinib in Imatinib-Resistant, BCR-ABL–Mutated CML
Blood, 2009 Sept 24, MC Muller, et al
Dasatinib elicited durable responses after prior imatinib failure in patients with CML-CP, regardless of BCR-ABL mutation status.
Weekly Journal ScansMore »
Impact of Age on Survival in Patients Undergoing Surgery for Gastroesophageal Cancer
Cancer, 2009 Oct 21, F Braiteh, et al
Patients ≤60 years of age had better OS and fewer surgical complications than did those >70 years.
Predicting Benefit From EGFR Inhibitors in HNSCC Free Full-Text PDF
Oral Oncol, 2009 Oct 1, EEW Cohen, et al
Older age, better performance status, and rash were linked to clinical benefit from EGFR treatment for head and neck cancer.
MDS Clinical Trial Design in the Era of New Therapy Options
Blood, 2009 Sept 24, MA Sekeres, et al
Clear definitions for prior treatment and disease progression will aid in designing clinical trials for new MDS agents.
Patient Perception and Adjuvant Therapy Use in Breast Cancer
J Clin Oncol, 2009 Sept 21, NA Bickell, et al
Underuse of adjuvant therapy for breast cancer is more common among patients with certain knowledge, beliefs, and attitudes.
Preoperative Chemotherapy Improves Long-Term Survival in Esophageal Cancer
J Clin Oncol, 2009 Sept 21, WH Allum, et al
Long-term follow-up confirmed the survival benefit of preoperative chemotherapy plus surgery in esophageal cancer.
Neoadjuvant Chemoradiotherapy Offers DFS, RFS Advantage in Locally Advanced Rectal Cancer
J Clin Oncol, 2009 Sept 21, MS Roh, et al
The NSABP R-03 trial demonstrated significantly improved DFS and RFS with neoadjuvant vs adjuvant chemoradiotherapy.
Exercise Is an Important Intervention for Lymphoma Patients
J Clin Oncol, 2009 Sept 20, K Courneya, et al
Exercise training during or after chemotherapy may provide physical and psychological benefits for patients with lymphoma.
Low p27 Expression Is Prognostic in Tamoxifen-Treated Postmenopausal HR+ Breast Cancer
Clin Cancer Res, 2009 Sept 15, M Filipits, et al
Low p27 expression predicted relapse and death in postmenopausal women with early HR+ breast cancer treated with long-term tamoxifen.
Rheumatologic Assessment of Arthralgia in Patients on Aromatase Inhibitors
J Clin Oncol, 2009 Sept 14, O Dizdar, et al
Approximately one-third of patients on AIs experienced arthralgia, many of whom had tenosynovial changes.
Bone Marrow Micrometastases and SLN Status in Early Breast Cancer Free Full-Text PDF
Breast Diseases: A Year Book Quarterly, 2009 Sept 1, AK Lodhi , et al
Commentary reviews evidence suggesting that BMM status adds prognostic information to sentinel lymph node status.
Review Article of the Week
Triple Negative Breast Cancers: Clinical and Prognostic Implications
Eur J Cancer, 2009 Sept 1, SJ Dawson, et al
The molecular and clinical features of triple-negative breast cancer may point the way to improved therapy.
Weekly Review ArticlesMore »
Drug Interactions Between Antineoplastic and Antiretroviral Therapies Free Full-Text PDF
Crit Rev Oncol Hematol, 2009 Oct 1, N Mounier, et al
Antineoplastic drugs used to treat HIV-related malignancies may interact, through the CYP system, with anti-HIV agents.
Toxicities of Treatment for Head and Neck Cancer Free Full-Text PDF
Oral Oncol, 2009 Oct 1, RM Logan
This review of toxicities to conventional and targeted therapies also discusses toxicity clusters and risk factors.
Chemotherapy in Stage III Non–Small Cell Lung Cancer
Eur J Cancer, 2009 Sept 1, WEE Eberhardt, et al
Relapse patterns, optimal indications, consolidation, new drug combinations, immunotherapy, and toxicity are discussed.
Molecular Biology and Therapy of Mantle Cell Lymphoma Free Full-Text PDF
Blood Rev, 2009 Sept 1, A Obrador-Hevia, et al
New drug classes that target key molecular pathways in mantle cell lymphoma may help to overcome treatment resistance.

ECCO/ESMO 2009
Conference news plus interviews with ECCO/ESMO officers.



Advertisement.
CANCER POLICY FORUM

Get behind-the-headline perspectives on the politics of cancer.

VISIT SITE
WHEN THE SMOKE CLEARS
Experts discuss the true clinical implications of watershed developments in oncology research.

VISIT SITE
RELATED WEBSITES
These websites offer more information on a variety of oncology-related topics.

VISIT SITE
VIDEOS
Watch video interviews with leading cancer experts.

VISIT SITE
Elsevier Inc. Home | Site Map | Cancer Types | About OncologySTAT | Privacy Policy | Terms of Use | Contact Us | Advertise

You are currently subscribed as %%email%% | Unsubscribe | Update Your Profile
Was this email forwarded to you? Sign-up for your own free subscription.
Copyright © 2012, Elsevier Inc. All rights reserved.
Elsevier Inc., 1600 John F. Kennedy Boulevard, Suite 1800.
Philadelphia, PA 19103-2899, USA