JOURNAL SCANS: REVIEW

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New Biologic Agents for the Treatment of Gynecologic Cancers

N Horowitz, UA Matulonis, 2012 Feb 1, Hematol Oncol Clin North Am

Abstract Improved understanding of the molecular basis of gynecologic cancers in addition to the availability of faster and less expensive technologies for genetic analysis of cancers has led to the exciting...

Primary Malignant Melanoma of Head and Neck: A Comprehensive Review of Literature

AK Vikey, D Vikey, 2012 Jan 20, Oral Oncol

Abstract Malignant melanoma has been considered a deadly disease for a long time; however, risk factors have been minimized due to substantial coverage in the literature, new technologies, and promising...

Target Therapy in Elderly Breast Cancer Patients

P Carli, E Turchet, D Quitadamo, D Crivellari, et al, 2012 Jan 16, Crit Rev Oncol Hematol

Abstract Substantial progress has been made in the management of breast cancer by targeting HER2 and VEGF pathways. Although the efficacy and safety of target therapy in breast cancer have been established,...

Radiomics: Extracting More Information From Medical Images Using Advanced Feature Analysis

P Lambin E Rios-Velazquez, R Leijenaar, H Aerts, et al, 2012 Jan 16, Eur J Cancer

Abstract Solid cancers are spatially and temporally heterogeneous. This limits the use of invasive biopsy based molecular assays but gives huge potential for medical imaging, which has the ability to capture...

Prognostic and Therapeutic Implications of Minimal Residual Disease Detection in Acute Myeloid Leukemia

F Buccisano, L Maurillo, MI Del Principe, A Venditti, et al, 2012 Jan 12, Blood

Abstract The choice of either induction or post-remission therapy for adults with acute myeloid leukemia is still largely based on the "one size fits all" principle. Moreover, pre-treatment prognostic...

Risk Factors for Acute GVHD and Survival After Hematopoietic Cell Transplantation

M Jagasia, M Arora, ME Flowers, T Hahn, et al, 2012 Jan 5, Blood

Abstract Risk factors for acute GVHD (AGVHD), overall survival, and transplant-related mortality were evaluated in adults receiving allogeneic hematopoietic cell transplants (1999-2005) from HLA-identical...

Metastatectomy for Extra-Cranial Extra-Adrenal Non-Small Cell Lung Cancer Solitary Metastases: Systematic Review and Analysis of Reported Cases

S Salah, T Tanvetyanon, S Abbasi, 2012 Jan 1, Lung Cancer

Abstract Background: Although patients with stage IV non-small cell lung cancer (NSCLC) have a poor prognosis, a subset of patients with solitary brain or adrenal metastasis have more favorable outcome...

Breast Cancer Occurred After Hodgkin's Disease: Clinico-Pathological Features, Treatments and Outcome: Analysis of 214 Cases

B Cutuli, S Kanoun, C Tunon De Lara, M Velten, 2012 Jan 1, Crit Rev Oncol Hematol

Abstract Background: Secondary tumours (ST) represent a major concern in survivors of Hodgkin's disease (HD). Breast cancer (BC) is the most frequent ST among young treated women.Material and Methods:...

Advanced Gastric Cancer and Cancer of the Gastro-Oesophageal Junction: Focus On Targeted Therapies

A Cappetta, S Lonardi, D Pastorelli, F Bergamo, G Lombardi, V Zagonel, 2012 Jan 1, Crit Rev Oncol Hematol

Abstract Despite recent improvements in surgical techniques and chemotherapy treatments, locally advanced/metastatic gastroesophageal junction (GEJ) and gastric cancer (GC) are still associated with poor...

Is It Time for Tailored Treatment of Rectal Cancer? From Prescribing by Consensus to Prescribing by Numbers

V Valentini, P Lambin, RJ Myerson, 2012 Jan 1, Radiother Oncol

Abstract In the past two decades a series of multi-institution clinical trials have done much to define the role of multi-modality treatment in the management of rectal adenocarcinoma. These trialshave...

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