REVIEW ARTICLES

Peruse thousands of cancer-specific review articles, most with full-text downloadable PDFs

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Genistein and hematological malignancies

Wang Li, Lynn T. Frame, Samantha Hirsch, Everardo Cobos, 2010 Oct 1, Cancer Lett

Journal Content Genistein is an isoflavanoid from soybeans and promising cancer chemotherapeutic agent. Genistein exposure varies widely because of cultural differences in diet. Hypothetically, this could...

Hunting for robust gene signature from cancer profiling data: Sources of variability, different interpretations, and recent methodological developments

Jian-zhen Xu, Chi-wai Wong, 2010 Oct 1, Cancer Lett

Journal Content Gene microarray is a powerful platform to investigate the expression patterns of thousands of genes simultaneously. One central objective of such analysis is to select sets of genes (i.e.,...

Molecular networks in respiratory epithelium carcinomas

Athanasios G. Pallis, Michalis V. Karamouzis, Panagiotis A. Konstantinopoulos, Athanasios G. Papavassiliou, 2010 Sept 1, Cancer Lett

Journal Content Current anti-cancer research is focused on cell surface receptors targeting, mainly epidermal growth factor receptor and vascular endothelial growth factor receptor, against which a few...

Cyclooxygenase-2 in tumorigenesis of gastrointestinal cancers: An update on the molecular mechanisms

William Ka Kei Wu, Joseph Jao Yiu Sung, Chung Wa Lee, Jun Yu, Chi Hin Cho, 2010 Sept 1, Cancer Lett

Journal Content The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with lower risks for esophageal, gastric and colon cancers as well as other solid tumors. The antitumor effect of...

Multidrug resistance in oral squamous cell carcinoma: The role of vacuolar ATPases

Mario Pérez-Sayáns, José Manuel Somoza-Martín, Francisco Barros-Angueira, Pilar Gayoso Diz, José Manuel Gándara Rey, Abel García-García, 2010 Sept 1, Cancer Lett

Journal Content Resistance to chemotherapy agents is the main reason for treatment failure in patients with cancer. Multidrug resistance (MDR) is the primary mechanism that leads to the acquisition of...

Combined proteasome and histone deacetylase inhibition: A promising synergy for patients with relapsed/refractory multiple myeloma

Sundar Jagannath, Meletios A. Dimopoulos, Sagar Lonial, 2010 Sept 1, Leuk Res

Journal Content Multiple myeloma (MM) is an incurable disease characterized by the accumulation of malignant plasma cells in the bone marrow. Recently, an improved understanding of the biology of the...

Lessons learnt from gefitinib and erlotinib: Key insights into small-molecule EGFR-targeted kinase inhibitors in non-small cell lung cancer

Eckart Laack, Guido Sauter, Carsten Bokemeyer, 2010 Sept 1, Lung Cancer

Journal Content Improving treatment options and patient outcomes for those with non-small cell lung cancer (NSCLC) represents a significant worldwide challenge. Although traditional treatment strategies...

Rationale of a relaunch of gefitinib in Caucasian non-small cell lung cancer patients

Andreas Pircher, Ferdinand Ploner, Helmut Popper, Wolfgang Hilbe, 2010 Sept 1, Lung Cancer

Journal Content In 2002 results of two-phase II studies with the new epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) gefitinib showed not only promising efficacy in second and...

Second-Look Targeted Studies After Breast Magnetic Resonance Imaging: Practical Tips to Improve Lesion Identification

Isabelle Trop, Maude Labelle, Julie David, Marie-Hélène Mayrand, Lucie Lalonde, 2010 Sept 1, Curr Probl Diagn Radiol

Journal Content Second-look studies, so-called because a re-evaluation of the breast is performed after review of magnetic resonance imaging (MRI) findings, offer the possibility of identifying correlates...

Spinal Cord Stimulation: The Types of Neurostimulation Devices Currently Being Used, and What Radiologists Need to Know When Evaluating Their Appearance on Imaging

Vivek Kalia, Cary Bizzell, Rick Obray, Jon Obray, Tim Lamer, John A. Carrino, 2010 Sept 1, Curr Probl Diagn Radiol

Journal Content Neural stimulation is increasingly used as a treatment for chronic pain. Common indications for spinal cord stimulation include chronic neuropathic and oncological pain, intractable angina,...

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