Radiation-Related Treatment Effects Across the Age Spectrum: Differences and Similarities or What the Old and Young Can Learn from Each Other

Semin Radiat Oncol. 2010 Jan;20(1):21-29, Matthew J. Krasin, Louis S. Constine, Debra L. Friedman, Lawrence B. Marks

Abstract

Abstract

Radiation related effects in children and adults limit the delivery of effective radiation doses and result in long-term morbidity affecting function and quality of life. Improvements in our understanding of the etiology and biology of these effects, including the influence of clinical variables, dosimetric factors, and the underlying biological processes have made treatment safer and more efficacious. However, the approach to studying and understanding these effects differs between children and...

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