Systemic Metabolic Radiopharmaceutical Therapy in the Treatment of Metastatic Bone Pain

Semin Nucl Med. 2010 Mar;40(2):89-104, Fabio M. Paes, Aldo N. Serafini

Abstract

Abstract

Bone pain due to skeletal metastases constitutes the most common type of chronic pain among patients with cancer. It significantly decreases the patient's quality of life and is associated with comorbidities, such as hypercalcemia, pathologic fractures and spinal cord compression. Approximately 65% of patients with prostate or breast cancer and 35% of those with advanced lung, thyroid, and kidney cancers will have symptomatic skeletal metastases. The management of bone pain is extremely difficult...

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