Peptide Receptor Radionuclide Therapy in Patients With Gastroenteropancreatic Neuroendocrine Tumors

Semin Nucl Med. 2010 Mar;40(2):78-88, Dik J. Kwekkeboom, Wouter W. de Herder, Casper H.J. van Eijck, Boen L. Kam, Martijn van Essen, Jaap J.M. Teunissen, Eric P. Krenning

Abstract

Abstract

Somatostatin receptor imaging with [111In-DTPA0)octreotide has proven its role in the diagnosis and staging of gastroenteropancreatic neuroendocrine tumors. Treatment with radiolabeled somatostatin analogues is a promising new tool in the management of patients with inoperable or metastasized, well-differentiated neuroendocrine tumors. Symptomatic improvement may occur with all 111In, 90Y, or 177Lu-labeled somatostatin analogues that have been used for peptide receptor radionuclide therapy. The results...

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