The contribution of the Epstein-Barr virus to the pathogenesis of childhood lymphomas
Fathima Zumla Cader, Pamela Kearns, Lawrence Young, Paul Murray, Martina Vockerodt
20100501
2010 Jun 1
Cancer Treat Rev
The contribution of the Epstein-Barr virus to the pathogenesis of childhood lymphomas
Cancer Treat Rev. 2010 Jun;36(4):348-353, Fathima Zumla Cader, Pamela Kearns, Lawrence Young, Paul Murray, Martina Vockerodt
Abstract
Abstract
The Epstein-Barr virus (EBV) is a lymphotropic herpes virus with oncogenetic properties which can lead to the development of lymphomas such as Burkitt’s lymphoma (BL), Hodgkin’s lymphoma (HL), or post-transplant lymphoma. This review discusses our current understanding of lymphomagenesis in relation to EBV and the potential for targeted therapies.
