Abstract

CommentaryThis work shows that a 4 “drug” regimen (“castration”, cytotoxoic virus, low dose docetaxol, 2–3 mk/kg, and a telomerase enzyme inhibitor via ‘antisense oligonucleotide’ to the binding site) can effectively limit or potentially cure the C4-2B cell line prostate cancer growth when used in the bone femur “met” model (similar to the British Journal of Cancer, Vessella and Corey study above). The drawback of the telomerase study above is that the virus is a potent cytotoxic and is not viable...