Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository

Urology. 2010 Feb;75(2):407-413, Lisa F. Newcomb, James D. Brooks, Peter R. Carroll, Ziding Feng, Martin E. Gleave, Peter S. Nelson, Ian M. Thompson, Daniel W. Lin

Abstract

Abstract

Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance...

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