Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository
Lisa F. Newcomb, James D. Brooks, Peter R. Carroll, Ziding Feng, Martin E. Gleave, Peter S. Nelson, Ian M. Thompson, Daniel W. Lin
20100101
2010 Feb 1
Urology
Canary Prostate Active Surveillance Study: Design of a Multi-institutional Active Surveillance Cohort and Biorepository
Urology. 2010 Feb;75(2):407-413, Lisa F. Newcomb, James D. Brooks, Peter R. Carroll, Ziding Feng, Martin E. Gleave, Peter S. Nelson, Ian M. Thompson, Daniel W. Lin
Abstract
Abstract
Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance...