Clinical Applications of a Peptide-Based Vaccine for Glioblastoma

Neurosurg Clin N Am. 2010 Jan;21(1):95-109, Charles W. Kanaly, Dale Ding, Amy B. Heimberger, John H. Sampson

ABSTRACT

Glioblastoma multiforme is a malignant, relentless brain cancer with no known cure, and standard therapies leave significant room for the development of better, more effective treatments. Immunotherapy is a promising approach to the treatment of solid tumors that directs the patient's own immune system to destroy tumor cells. The most successful immunologically based cancer therapy to date involves the passive administration of monoclonal antibodies, but significant antitumor responses have also...

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