The role of βIII tubulin in predicting chemoresistance in non-small cell lung cancer
Pascal Sève, Tony Reiman, Charles Dumontet
20100101
2010 Feb 1
Lung Cancer
The role of βIII tubulin in predicting chemoresistance in non-small cell lung cancer
Lung Cancer. 2010 Feb;67(2):136-143, Pascal Sève, Tony Reiman, Charles Dumontet
Abstract
Abstract
Lung cancer is a leading cause of death among adults. Non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases. For more than half of all patients diagnosis does not occur until the disease has metastasised. At this advanced stage, the 5-year survival rate is just 15%. Platinum-based chemotherapy forms the backbone of treatment for patients with advanced NSCLC and forms an important component of the therapeutic regimen for many patients with earlier stage disease. However, although...
