Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects
Katherine A Janeway, Holcombe E Grier
20100601
2010 Jul 1
Lancet Oncol
Sequelae of osteosarcoma medical therapy: a review of rare acute toxicities and late effects
Lancet Oncol. 2010 Jul;11(7):670-678, Katherine A Janeway, Holcombe E Grier
Abstract
Abstract
Since the introduction of multi-agent chemotherapy for osteosarcoma over 30 years ago, overall survival has exceeded 50%. A clear understanding of the acute complications and late effects of osteosarcoma therapy is required to care effectively for patients with osteosarcoma undergoing active treatment, and for the increasing number of osteosarcoma survivors. There has now been sufficient cumulative experience treating patients with osteosarcoma with active anti-osteosarcoma chemotherapy agents,...
