Radiation-Related Heart Disease: Current Knowledge and Future Prospects
Radiation-Related Heart Disease: Current Knowledge and Future Prospects
SC Darby, DJ Cutter, M Boerma, LS Constine, LF Fajardo, K Kodama, K Mabuchi, LB Marks, FA Mettler, LJ Pierce, KR Trott, ETH Yeh, RE Shore
Yes
20100201
2010 Mar 1
Int J Radiat Oncol Biol Phys
Radiation-Related Heart Disease: Current Knowledge and Future Prospects
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3):656-665, SC Darby, DJ Cutter, M Boerma, LS Constine, LF Fajardo, K Kodama, K Mabuchi, LB Marks, FA Mettler, LJ Pierce, KR Trott, ETH Yeh, RE Shore
Abstract
Abstract
It has been recognized since the 1960s that the heart may be damaged by substantial doses of radiation [>30 Gray (Gy)], such as used to occur during mantle radiotherapy for Hodgkin lymphoma. During the last few years, however, evidence that radiation-related heart disease (RRHD) can occur following doses below 20 Gy has emerged from several independent sources. Those sources include studies of breast cancer patients who received mean cardiac doses of 3 to 17 Gy when given radiotherapy following surgery...
