Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment: A Clinical Perspective
Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Cancer Treatment
SK Sandhu, TA Yap, JS de Bono
Yes
20100001
2010 Jan 1
Eur J Cancer
Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment: A Clinical Perspective
Eur J Cancer. 2010 Jan 1;46(1):9-20, SK Sandhu, TA Yap, JS de Bono
Abstract
Abstract
PARP inhibitors demonstrate single-agent antitumour activity in DNA-repair–defective tumors and a wide therapeutic index.
