Alpha-Fetoprotein-Producing Non-Germ Cell Tumours of the Female Genital Tract

Eur J Cancer. 2009 Feb 23; Epub online ahead of print, M El-Bahrawy

ABSTRACT

Elevated levels of alpha-fetoprotein (AFP), a foetal serum protein, occur mainly on the development of hepatocellular carcinoma (HCC) or germ cell tumours, including yolk sac tumour (YST) and embryonal carcinoma of the ovary. Rarely, other tumours of the female genital tract produce AFP. This article reviews the AFP-producing non-germ cell tumours reported in different parts of the female genital tract to date. These include different types of carcinomas and carcinosarcomas of the uterus, ovary and...

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