Molecular networks in respiratory epithelium carcinomas
Athanasios G. Pallis, Michalis V. Karamouzis, Panagiotis A. Konstantinopoulos, Athanasios G. Papavassiliou
20100801
2010 Sept 1
Cancer Lett
Molecular networks in respiratory epithelium carcinomas
Cancer Lett. 2010 Sept 01;295(1):1-6, Athanasios G. Pallis, Michalis V. Karamouzis, Panagiotis A. Konstantinopoulos, Athanasios G. Papavassiliou
Abstract
Abstract
Current anti-cancer research is focused on cell surface receptors targeting, mainly epidermal growth factor receptor and vascular endothelial growth factor receptor, against which a few targeted agents are now available in clinical practice. Recent improvements of our understanding on the intracellular networks that participate in respiratory epithelium carcinogenesis have further elucidated the role of a variety of molecules that represent attractive targets for novel therapeutic strategies. The...
