Ultrasound Morphology Criteria Predict Metastatic Disease of the Sentinel Nodes in Patients With Melanoma

J Clin Oncol. 2010 Jan 11;[Epub Ahead of Print], C Voit, AC Van Akkooi, G Schäfer-Hesterberg, A Schoengen, K Kowalczyk, JC Roewert, W Sterry, AM Eggermont

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Abstract

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OncologySTAT Editorial Team

Regional lymph node involvement is a key indicator of overall survival (OS) in patients with stage I and II melanoma. Sentinel node (SN) biopsy is used to identify metastases early. Ultrasound (US)-guided fine needle aspiration cytology (FNAC) is highly sensitive and specific for identifying regional metastases. One study showed that US-FNAC identified 65% of SN metastases before surgery, reducing the number of SN procedures by 13%. In the present study, Voit et al investigated US morphology patterns...

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