Journal Scans
Treatment of Favorable, Limited-Stage Hodgkin's Lymphoma With Chemotherapy Without Consolidation by Radiation Therapy
Chemotherapy Alone Is Effective in Nonbulky, Early Hodgkin's Lymphoma
GP Canellos, JS Abramson, DC Fisher, AS Lacasce
20100116
2010 Feb 16
J Clin Oncol
Treatment of Favorable, Limited-Stage Hodgkin's Lymphoma With Chemotherapy Without Consolidation by Radiation Therapy
J Clin Oncol. 2010 Feb 16;[Epub Ahead of Print], GP Canellos, JS Abramson, DC Fisher, AS Lacasce
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
In patients with early Hodgkin’s lymphoma (HL), the addition of chemotherapy to radiation therapy (RT) significantly decreases the incidence of relapse. However, long-term sequelae of RT in these patients, who are typically young when diagnosed, include an increased risk of cardiac complications and secondary malignancies. Thus, use of a treatment strategy consisting of chemotherapy without RT has been explored. In this retrospective analysis of patients with limited-stage disease, Harvard Medical...
