Journal Scans
Surgical Treatment of Gastric Cancer: 15-year Follow-up Results of the Randomised Nationwide Dutch D1D2 Trial
Surgical Treatment of Gastric Cancer: D1D2 Study 15-year Follow-up
I Songun, H Putter, E Meershoek-Klein Kranenbarg, M Sasako, CJH van de Velde
20100320
2010 Apr 20
Lancet Oncol
Surgical Treatment of Gastric Cancer: 15-year Follow-up Results of the Randomised Nationwide Dutch D1D2 Trial
Lancet Oncol. 2010 Apr 20; Epub ahead of print, I Songun, H Putter, E Meershoek-Klein Kranenbarg, M Sasako, CJH van de Velde
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Abstract
Abstract
Background: Historical data and recent studies show that standardised extended (D2) lymphadenectomy leads to better results than standardised limited (D1) lymphadenectomy. Based on these findings, the Dutch D1D2 trial, a nationwide prospectively randomised clinical trial, was undertaken to compare D2 with D1 lymphadenectomy in patients with resectable primary adenocarcinoma of the stomach. The aim of the study was to assess the effect of D2 compared with D1 surgery on disease recurrence and survival...