Journal Scans
Surgery With Curative-Intent in Patients Treated With First-Line Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer. First BEAT and the Randomised Phase-III NO16966 Trial
Curative Surgery in Metastatic CRC Treated With Bevacizumab
A Okines, O del Puerto, D Cunningham, I Chau, E Van Cutsem, L Saltz, J Cassidy
20090906
2009 Oct 6
Br J Cancer
Surgery With Curative-Intent in Patients Treated With First-Line Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer. First BEAT and the Randomised Phase-III NO16966 Trial
Br J Cancer. 2009 Oct 6;101(7):1033-1038, A Okines, O del Puerto, D Cunningham, I Chau, E Van Cutsem, L Saltz, J Cassidy
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Abstract
Abstract
Background: Complete resection of metastases can result in cure for selected patients with metastatic colorectal cancer. Methods: First BEAT evaluated the safety of bevacizumab with first-line chemotherapy in 1914 patients. Prospectively collected data from 225 patients who underwent curative-intent surgery were analysed, including an exploratory comparison of resection rate in patients treated with different regimens. NO16966 compared efficacy of oxaliplatin-based chemotherapy plus bevacizumab...
