Journal Scans
Size of Sentinel-Node Metastasis and Chances of Non-Sentinel-Node Involvement and Survival in Early Stage Vulvar Cancer: Results From GROINSS-V, a Multicentre Observational Study
Size of Sentinel-Node Metastasis in Vulvar Cancer
MH Oonk, BM van Hemel, H Hollema, JA de Hullu, AC Ansink, I Vergote, RH Verheijen, A Maggioni, KN Gaarenstroom, PJ Baldwin, EB van Dorst, J van der Velden, RH Hermans, H W van der Putten, P Drouin, IB Runnebaum, WJ Sluiter, AG van der Zee
20100426
2010 May 26
Lancet Oncol
Size of Sentinel-Node Metastasis and Chances of Non-Sentinel-Node Involvement and Survival in Early Stage Vulvar Cancer: Results From GROINSS-V, a Multicentre Observational Study
Lancet Oncol. 2010 May 26;[Epub Ahead of Print], MH Oonk, BM van Hemel, H Hollema, JA de Hullu, AC Ansink, I Vergote, RH Verheijen, A Maggioni, KN Gaarenstroom, PJ Baldwin, EB van Dorst, J van der Velden, RH Hermans, H W van der Putten, P Drouin, IB Runnebaum, WJ Sluiter, AG van der Zee
TAKE-HOME MESSAGE
Abstract
Abstract
Background: Currently, all patients with vulvar cancer with a positive sentinel node undergo inguinofemoral lymphadenectomy, irrespective of the size of sentinel-node metastases. Our study aimed to assess the association between size of sentinel-node metastasis and risk of metastases in non-sentinel nodes, and risk of disease-specific survival in early stage vulvar cancer. Methods: In the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V), sentinel-node detection was done...
