Journal Scans
Significantly Higher Levels of Vascular Endothelial Growth Factor (VEGF) and Shorter Survival Times for Patients With Primary Operable Triple-Negative Breast Cancer
Triple-Negative Breast Cancer Has Higher VEGF Levels and Worse Prognosis
BK Linderholm, H Hellborg, U Johansson, G Elmberger, L Skoog, J Lehtiö, R Lewensohn
20090901
2009 Oct 1
Ann Oncol
Significantly Higher Levels of Vascular Endothelial Growth Factor (VEGF) and Shorter Survival Times for Patients With Primary Operable Triple-Negative Breast Cancer
Ann Oncol. 2009 Oct 1;20(10):1639-1646, BK Linderholm, H Hellborg, U Johansson, G Elmberger, L Skoog, J Lehtiö, R Lewensohn
TAKE-HOME MESSAGE
Abstract
SUMMARY
OncologySTAT Editorial Team
Triple-negative breast cancer (TBNC), which lacks expression of estrogen receptors (ER) and progesterone receptors (PR), as well as of human epidermal growth factor receptor 2 (HER2), is associated with much poorer prognosis than are other types of breast cancer. Increased expression of another growth factor receptor, vascular endothelial growth factor (VEGF), has been associated with poor prognosis in breast cancer and other types of cancer. This study evaluated the relationships between VEGF levels...
