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Sentinel Lymph Node Biopsy Accurately Stages the Regional Lymph Nodes for T1-T2 Oral Squamous Cell Carcinomas: Results of a Prospective Multi-Institutional Trial
SLNB Proves Accurate in Early Oral Cancer
FJ Civantos, RP Zitsch, DE Schuller, A Agrawal, RB Smith, R Nason, G Petruzelli, CG Gourin, RJ Wong, RL Ferris, A El Naggar, JA Ridge, RC Paniello, K Owzar, L McCall, DB Chepeha, WG Yarbrough, JN Myers
20100108
2010 Feb 8
J Clin Oncol
Sentinel Lymph Node Biopsy Accurately Stages the Regional Lymph Nodes for T1-T2 Oral Squamous Cell Carcinomas: Results of a Prospective Multi-Institutional Trial
J Clin Oncol. 2010 Feb 8; Epub ahead of print, FJ Civantos, RP Zitsch, DE Schuller, A Agrawal, RB Smith, R Nason, G Petruzelli, CG Gourin, RJ Wong, RL Ferris, A El Naggar, JA Ridge, RC Paniello, K Owzar, L McCall, DB Chepeha, WG Yarbrough, JN Myers
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Abstract
SUMMARY
OncologySTAT Editorial Team
Prevention of lymphatic metastases is important in patients with early oral cancers, but such metastases will develop in only 20% to 30% of these patients. Although watchful waiting is an option, most patients undergo selective neck resection. Resection increases morbidity, however, and is unnecessary in the 70% to 80% of patients found to be lymph node negative on pathology. An intermediate option is sentinel lymph node biopsy (SLNB). This study showed that positive findings on SLNB indicate the...
