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Second Primary Cancer Risk of Radiation Therapy After Radical Prostatectomy for Prostate Cancer: An Analysis of SEER Data
RT After Radical Prostatectomy Raises Risk of Second Primary Cancer
M Abdel-Wahab, IM Reis, J Wu, R Duncan
20090901
2009 Oct 1
Urology
Second Primary Cancer Risk of Radiation Therapy After Radical Prostatectomy for Prostate Cancer: An Analysis of SEER Data
Urology. 2009 Oct 1;[Epub Ahead of Print], M Abdel-Wahab, IM Reis, J Wu, R Duncan
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Abstract
Abstract
Objectives: To determine the incidence of second primary cancer (SPC) and primary pelvic late SPC/radiation-induced SPC after radical prostatectomy and radiation. Methods: A total of 228 235 prostate cancer patients in the 1973-2002 Surveillance, Epidemiology, and End Results database were studied. The age-adjusted estimates of SPCs was calculated. Competing risk multivariable Cox proportional hazards regression analysis was adjusted for age at diagnosis, race or ethnicity, and radiation and was...