Salvage Chemotherapy With Alternating MINE–ESHAP Regimen in Relapsed or Refractory Hodgkin's Lymphoma Followed by Autologous Stem-Cell Transplantation

Ann Oncol. 2010 Jun 1;[Epub Ahead of Print], C Fernández de Larrea, C Martínez, A Gaya, A López-Guillermo, M Rovira, F Fernández-Avilés, M Lozano, F Bosch, J Esteve, B Nomdedeu, E Montserrat, E Carreras

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Abstract

SUMMARY

OncologySTAT Editorial Team

The gold standard for patients with relapsed/refractory Hodgkin’s lymphoma (HL) is high-dose chemotherapy (HDT) followed by autologous stem-cell transplantation (ASCT). The best pretransplantation salvage chemotherapy regimen would combine therapeutic activity, stem-cell mobilizing potential, and low toxicity. However, the optimal salvage regimen has not been identified through randomized trials. Researchers from Barcelona retrospectively reviewed 61 relapsed/refractory HL cases treated from 2000...

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