Risk of Fracture After Single Fraction Image-Guided Intensity-Modulated Radiation Therapy to Spinal Metastases

J Clin Oncol. 2009 Sept 8;[Epub Ahead of Print], PS Rose, I Laufer, PJ Boland, A Hanover, MH Bilsky, J Yamada, E Lis

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Abstract

SUMMARY

OncologySTAT Editorial Team

Spinal metastasis is normally treated with radiation therapy (RT), surgery, or a combination of both. Recent development of image-guided intensity modulated RT (IG-IMRT) allows cancers that are traditionally radioresistant to be treated with a -high-dose single fraction. Anecdotal evidence suggests that patients who undergo IMRT may be at risk for vertebral fractures, although specifically which patients are at increased risk is unclear. In this single-center study of patients treated at Memorial...

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