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Risk Factors for Prostate Cancer Detection After a Negative Biopsy: A Novel Multivariable Longitudinal Approach
Time-Dependent Factors Can Stratify Risk of Prostate Cancer
PH Gann, A Fought, R Deaton, WJ Catalona, E Vonesh
20100122
2010 Feb 22
J Clin Oncol
Risk Factors for Prostate Cancer Detection After a Negative Biopsy: A Novel Multivariable Longitudinal Approach
J Clin Oncol. 2010 Feb 22;[Epub Ahead of Print], PH Gann, A Fought, R Deaton, WJ Catalona, E Vonesh
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Abstract
SUMMARY
OncologySTAT Editorial Team
Prostate biopsy is performed based on prostate-specific antigen (PSA) testing, but negative results from a biopsy do not rule out prostate cancer. At present, no reliable protocol exists for stratifying which patients may benefit from further follow-up biopsies. This study, reported by Gann et al, used longitudinal data from a large cohort to identify changes in risk factors for prostate cancer over time following a negative biopsy. Using these data, the authors developed a new model for discerning...
