Prospective Assessment of GI and GU Toxicity of Salvage Radiotherapy for Patients With PSA Relapse or Local Recurrence After Radical Prostatectomy

Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):792-798, M Pearse, R Choo, C Danjoux, S Gardner, G Morton, E Szumacher, A Loblaw, P Cheung

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Abstract

Abstract

Purpose: To assess the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity of salvage radiotherapy (RT). Methods and Materials: A total of 75 patients with prostate-specific antigen relapse or clinically isolated local recurrence after radical prostatectomy were accrued between 1998 and 2002 for a Phase II study to evaluate the efficacy of salvage RT plus 2-year androgen suppression. Acute and late GI and GU toxicity was prospectively assessed using the National Cancer Institute...

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