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Prospective Assessment of GI and GU Toxicity of Salvage Radiotherapy for Patients With PSA Relapse or Local Recurrence After Radical Prostatectomy
Late GI and GU Toxicity After Salvage RT for Prostate Cancer
M Pearse, R Choo, C Danjoux, S Gardner, G Morton, E Szumacher, A Loblaw, P Cheung
20081001
2008 Nov 1
Int J Radiat Oncol Biol Phys
Prospective Assessment of GI and GU Toxicity of Salvage Radiotherapy for Patients With PSA Relapse or Local Recurrence After Radical Prostatectomy
Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):792-798, M Pearse, R Choo, C Danjoux, S Gardner, G Morton, E Szumacher, A Loblaw, P Cheung
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Abstract
Abstract
Purpose: To assess the acute and late gastrointestinal (GI) and genitourinary (GU) toxicity of salvage radiotherapy (RT). Methods and Materials: A total of 75 patients with prostate-specific antigen relapse or clinically isolated local recurrence after radical prostatectomy were accrued between 1998 and 2002 for a Phase II study to evaluate the efficacy of salvage RT plus 2-year androgen suppression. Acute and late GI and GU toxicity was prospectively assessed using the National Cancer Institute...