Predictors of Recurrence in Breast Cancer Patients With a Pathologic Complete Response After Neoadjuvant Chemotherapy

Br J Cancer. 2010 Jul 27;103(3):297-302, M Tanioka, C Shimizu, K Yonemori, K Yoshimura, K mTamura, T Kouno, M Ando, N Katsumata, H Tsuda, T Kinoshita, Y Fujiwara

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Abstract

Abstract

Background: Although a pathologic complete response (pCR) after neoadjuvant chemotherapy is associated with favourable outcomes, a small proportion of patients with pCR have recurrence. This study was designed to identify factors predictive of recurrence in patients with pCR. Methods: A total of 449 breast cancer patients received neoadjuvant chemotherapy, and 88 evaluable patients had a pCR, defined as no evidence of invasive carcinoma in the breast at surgery. The clinical stage was II in 61 patients...

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