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Outcomes After Stereotactic Lung Radiotherapy or Wedge Resection for Stage I Non–Small-Cell Lung Cancer
Stereotactic Radiotherapy vs Wedge Resection in Early NSCLC
IS Grills, VS Mangona, R Welsh, G Chmielewski, E McInerney, S Martin, J Wloch, H Ye, LL Kestin
20100011
2010 Jan 11
J Clin Oncol
Outcomes After Stereotactic Lung Radiotherapy or Wedge Resection for Stage I Non–Small-Cell Lung Cancer
J Clin Oncol. 2010 Jan 11; Epub ahead of print, IS Grills, VS Mangona, R Welsh, G Chmielewski, E McInerney, S Martin, J Wloch, H Ye, LL Kestin
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Abstract
SUMMARY
OncologySTAT Editorial Team
Surgery is considered standard treatment for resectable stage I non–small-cell lung cancer (NSCLC). In patients with inoperable tumors, fractionated radiotherapy (RT) of 60 to 70 Gy is recommended. Recent evidence suggests that stereotactic body radiation therapy (SBRT) can greatly improve local control. Local control rates of 85% to 95% have been reported in patients with unresectable stage I tumors. Thus, the treatment paradigm has changed to standard SBRT in this setting. In this single-center...
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