Outcome of Transplantation for Myelofibrosis

Biol Blood Marrow Transplant. 2010 Mar 1;16(3):358-367, KK Ballen, S Shrestha, KA Sobocinski, M-J Zhang, A Bashey, BJ Bolwell, F Cervantes, SM Devine, RP Gale, V Gupta, TE Hahn, WJ Hogan, N Kröger, MR Litzow, DI Marks, RT Maziarz, PL McCarthy, G Schiller, HC Schouten, V Roy, PH Wiernik, MM Horowitz, SA Giralt, M Arora

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Abstract

Abstract

Myelofibrosis is a myeloproliferative disorder incurable with conventional strategies. Several small series have reported long-term disease-free survival (DSF) after allogeneic hematopoietic cell transplantatio(HCT). In this study, we analyze the outcomes of 289 patients receiving allogeneic transplantation for primary myelofibrosis between 1989 and 2002, from the database of the Center for International Bone Marrow Transplant Research (CIBMTR). The median age was 47 years (range: 18-73 years). Donors...

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