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Negative Helicobacter pylori Status Is Associated With Poor Prognosis in Patients With Gastric Cancer
Prognostic Significance of H. pylori Status in Gastric Cancer
D Marrelli, C Pedrazzani, A Berardi, G Corso, A Neri, L Garosi, C Vindigni, A Santucci, N Figura, F Roviello
20090415
2009 May 15
Cancer
Negative Helicobacter pylori Status Is Associated With Poor Prognosis in Patients With Gastric Cancer
Cancer. 2009 May 15;115(10):2071-2080, D Marrelli, C Pedrazzani, A Berardi, G Corso, A Neri, L Garosi, C Vindigni, A Santucci, N Figura, F Roviello
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Abstract
Abstract
BACKGROUND: Recent studies have suggested that Helicobacter pylori (H. pylori) infection may be related to better prognosis in patients with gastric cancer, but to the authors' knowledge, this finding has not yet been validated. In the current study, the association between H. pylori status and clinical outcome was investigated in a large cohort of patients. METHODS: Frozen non-neoplastic gastric mucosa and serum samples obtained from 297 patients who underwent surgery for primary gastric cancer...
