Journal Scans
Multi-centre Phase II Clinical Trial of Yttrium-90 Resin Microspheres Alone in Unresectable, Chemotherapy Refractory Colorectal Liver Metastases
90Y Radioembolization Invokes Responses in Refractory CRC Hepatic Metastases
M Cosimelli, R Golfieri, PP Cagol, L Carpanese, R Sciuto, CL Maini, R Mancini, I Sperduti, G Pizzi, MG Diodoro, M Perrone, E Giampalma, B Angelelli, F Fiore, S Lastoria, S Bacchetti, D Gasperini, O Geatti, F Izzo, Italian Society of Locoregional Therapies in Oncology (SITILO)
20100627
2010 Jul 27
Br J Cancer
Multi-centre Phase II Clinical Trial of Yttrium-90 Resin Microspheres Alone in Unresectable, Chemotherapy Refractory Colorectal Liver Metastases
Br J Cancer. 2010 Jul 27;103(3):324-331, M Cosimelli, R Golfieri, PP Cagol, L Carpanese, R Sciuto, CL Maini, R Mancini, I Sperduti, G Pizzi, MG Diodoro, M Perrone, E Giampalma, B Angelelli, F Fiore, S Lastoria, S Bacchetti, D Gasperini, O Geatti, F Izzo, Italian Society of Locoregional Therapies in Oncology (SITILO)
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Abstract
SUMMARY
OncologySTAT Editorial Team
Most patients with advanced colorectal cancer (CRC) who have unresectable liver metastases will develop recurrence after treatment with chemotherapy. In cases where metastases are inoperable, radioembolization using yttrium-90 (90Y) microspheres can be used, either with chemotherapy or alone, to deliver radiation therapy to hepatic lesions. In this minimally invasive approach, the microspheres are delivered via a transfemoral catheter through the hepatic artery branches and then to the neovascular...
