Journal Scans
Lynch Syndrome Among Gynecologic Oncology Patients Meeting Bethesda Guidelines for Screening
Lynch Syndrome Among Gynecologic Oncology Patients
CS Walsh, A Blum, A Walts, R Alsabeh, H Tran, HP Koeffler, BY Karlan
20100201
2010 Mar 1
Gynecol Oncol
Lynch Syndrome Among Gynecologic Oncology Patients Meeting Bethesda Guidelines for Screening
Gynecol Oncol. 2010 Mar 1;116(3):516-521, CS Walsh, A Blum, A Walts, R Alsabeh, H Tran, HP Koeffler, BY Karlan
TAKE-HOME MESSAGE
Abstract
Abstract
Objective: Lynch syndrome (LS) is characterized by a high lifetime incidence of colorectal cancer and gynecologic malignancies such as endometrial and ovarian cancer. Identification of LS families is important as it allows for heightened cancer screening which decreases colorectal cancer mortality. The original 1996 Bethesda guidelines included two gynecologic populations that should be further evaluated for LS: those with endometrial cancer before the age of 45 years and those with two LS-related...
