Journal Scans
Lack of Evidence for Fracture Prevention in Early Breast Cancer Bisphosphonate Trials: A Meta-analysis
No Fracture Prevention With Bisphosphonates for Breast Cancer
A Valachis, NP Polyzos, V Georgοulias, D Mavroudis, D Mauri
20100301
2010 Apr 1
Gynecol Oncol
Lack of Evidence for Fracture Prevention in Early Breast Cancer Bisphosphonate Trials: A Meta-analysis
Gynecol Oncol. 2010 Apr 1;117(1):139-145, A Valachis, NP Polyzos, V Georgοulias, D Mavroudis, D Mauri
Abstract
Abstract
Objectives: Recent data suggest that fractures might affect quality of life and survival in early breast cancer patients. Bisphosphonates are effective in treatment and prevention of cancer treatment-induced bone loss, but their value in the prevention of fractures is still investigational. Our aim was to evaluate the fracture rate in breast cancer patients receiving adjuvant bisphosphonates compared with those receiving no treatment or placebo. Methods: Our study is a systematic review and meta-analysis...
