Intraoperative MRI Guidance And Extent Of Resection In Glioma Surgery: A Randomised, Controlled Trial

Lancet Oncol. 2011 Aug 23;[Epub Ahead of Print], C Senft, A Bink, K Franz, H Vatter, T Gasser, V Seifert

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Abstract

Abstract

Background: Intraoperative MRI is increasingly used in neurosurgery, although there is little evidence for its use. We aimed to assess efficacy of intraoperative MRI guidance on extent of resection in patients with glioma.Methods: In our prospective, randomised, parallel-group trial, we enrolled adults (≥18 years) with contrast enhancing gliomas amenable to radiologically complete resection who presented to Goethe University (Frankfurt, Germany). We randomly assigned patients (1:1) with computer-generated...

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