Incidence of Adenocarcinoma Among Patients With Barrett's Esophagus

N Engl J Med. 2011 Oct 13;3651375-1383, F Hvid-Jensen, L Pedersen, AM Drewes, HT Sorensen, P Funch-Jensen

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OncologySTAT Editorial Team

Barrett’s esophagus is thought to be a precursor lesion in most cases of esophageal adenocarcinoma, transitioning to cancer through low-grade and high-grade dysplasia. This is the basis for current endoscopic surveillance guidelines for patients with Barrett’s esophagus. However, an estimated 95% of patients with newly diagnosed esophageal adenocarcinoma have no history of Barrett’s esophagus, and there are no studies showing that surveillance programs in patients with Barrett’s esophagus affect...

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