Journal Scans
High-Dose Chemotherapy With Blood or Bone Marrow Transplants for Rhabdomyosarcoma
High-Dose Chemotherapy With Transplants for Rhabdomyosarcoma
PJ Stiff, M-A Agovi, KH Antman, D Blaise, BM Camitta, MS Cairo, RW Childs, JR Edwards, RP Gale, GA Hale, HM Lazarus, M Arora
20100301
2010 Apr 1
Biol Blood Marrow Transplant
High-Dose Chemotherapy With Blood or Bone Marrow Transplants for Rhabdomyosarcoma
Biol Blood Marrow Transplant. 2010 Apr 1;16(4):525-532, PJ Stiff, M-A Agovi, KH Antman, D Blaise, BM Camitta, MS Cairo, RW Childs, JR Edwards, RP Gale, GA Hale, HM Lazarus, M Arora
TAKE-HOME MESSAGE
Abstract
Abstract
Rhabdomyosarcoma (RMS), the most common soft-tissue sarcoma in children, is cured with conventional therapy in 70%. However, the 5-year survival for those who relapse is about 30%, and drops to about 15% for those with unfavorable histologies (alveolar/undifferentiated subtypes). We describe outcomes of 62 subjects receiving autologous blood/bone marrow (BM) transplants for RMS between 1989 and 2003, and reported to the Center for International Blood and Marrow Transplantation Research (CIBMTR)....