Journal Scans
Functional Role and Prognostic Significance of CD157 in Ovarian Carcinoma
CD157 Linked to Tumor Invasion and Survival in Ovarian Cancer
E Ortolan, R Arisio, S Morone, P Bovino, N Lo-Buono, G Nacci, R Parrotta, D Katsaros, I Rapa, G Migliaretti, E Ferrero, M Volante, A Funaro
20100704
2010 Aug 4
J Natl Cancer Inst
Functional Role and Prognostic Significance of CD157 in Ovarian Carcinoma
J Natl Cancer Inst. 2010 Aug 4;102(15):1160-1177, E Ortolan, R Arisio, S Morone, P Bovino, N Lo-Buono, G Nacci, R Parrotta, D Katsaros, I Rapa, G Migliaretti, E Ferrero, M Volante, A Funaro
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Abstract
SUMMARY
OncologySTAT Editorial Team
CD157 is expressed by mesothelial cells and mediates leukocyte adhesion and migration. Recent evidence shows that CD157 genes are differentially expressed in epithelial ovarian cancer cells vs normal ovarian cells. This study evaluated several aspects of CD157 expression and behavior that supported the hypothesis that CD157 is involved in interactions between the mesothelium and ovarian tumor cells that might control ovarian cancer invasion and metastasis. CD157 may thus be a useful diagnostic marker...
