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Frequency of Screening Magnetic Resonance Imaging to Detect Occult Spinal Cord Compromise and to Prevent Neurological Deficit in Metastatic Castration-Resistant Prostate Cancer
MRI Detection of Occult Spinal Cord Compromise in Prostate Cancer
R Venkitaraman, SA Sohaib, Y Barbachano, CC Parker, RA Huddart, A Horwich, D Dearnaley
20100201
2010 Mar 1
Clin Oncol
Frequency of Screening Magnetic Resonance Imaging to Detect Occult Spinal Cord Compromise and to Prevent Neurological Deficit in Metastatic Castration-Resistant Prostate Cancer
Clin Oncol. 2010 Mar 1;22(2):147-152, R Venkitaraman, SA Sohaib, Y Barbachano, CC Parker, RA Huddart, A Horwich, D Dearnaley
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Abstract
Abstract
Aims: Neurological deficit from malignant spinal cord compression (SCC) is a major complication of metastatic castration-resistant prostate cancer (CRPC). The aims of the present study were to determine the incidence of neurological deficit in metastatic prostate cancer patients and to determine the optimal frequency of screening magnetic resonance imaging (MRI) spine required to detect clinically occult radiological SCC (rSCC). Materials and Methods: A retrospective analysis of the clinical data...