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FISH Analysis in Addition to G-Band Karyotyping: Utility in Evaluation of Myelodysplastic Syndromes?
FISH Analysis in Evaluation of Myelodysplastic Syndromes
W Yang, B Stotler, DW Sevilla, FN Emmons, VV Murty, B Alobeid, G Bhagat
20100301
2010 Apr 1
Leuk Res
FISH Analysis in Addition to G-Band Karyotyping: Utility in Evaluation of Myelodysplastic Syndromes?
Leuk Res. 2010 Apr 1;34(4):420-425, W Yang, B Stotler, DW Sevilla, FN Emmons, VV Murty, B Alobeid, G Bhagat
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Abstract
Abstract
Cytogenetic analysis provides important diagnostic and prognostic information for patients with myelodysplastic syndromes (MDS). Prior studies, mostly comprised of small sample sizes, have reported conflicting results while evaluating the usefulness of FISH in addition to G-band karyotyping in MDS. In the current study, the utility of performing a tailored FISH panel, in addition to G-band karyotyping was evaluated in a series of 110 MDS patients diagnosed at our institute. Using our FISH panel,...